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1.6.1

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@nuno-agostinho nuno-agostinho released this 05 Jul 15:50
946af16
  • Improve support for analysing SRA and user-owned data:
    • New tutorial on performing alternative splicing analysis using SRA and user-owned data from FASTQ files (other tutorials were also updated)
    • Process gene and splice junction counts from STAR output for subsequent loading into psichomics
    • Automatically download and load data from select SRA projects using the recount R package
  • Data grouping:
    • Preview groups based on selected attribute before creation
  • Gene, transcript and protein information:
    • Display alternative splicing events in transcript plot
  • Correlation between gene expression and alternative splicing:
    • Allow to change plot height and font size

Bug fixes and minor changes

  • Support new version of Human (hg38 assembly) alternative splicing annotation (fixes wrong coordinates for many minus-strand splicing events)
  • Fix issues with TCGA sample metadata:
    • No sample metadata loaded when loading TCGA files from local folder
    • Not retrieving sample metadata for all TCGA samples when multiple junction quantification files are loaded
  • Data grouping:
    • Correctly suggest how to select variables in subset expression and give more examples on how to use this feature
    • Fix subject/sample attributes not being updated for selection for the GREP interface
    • Fix error alerts not appearing when trying to create groups based on invalid parameters
    • Add an error alert when trying to extract group data from an user-provided file without such information
  • Alternative splicing quantification:
    • Fix crash when quantifying splicing for a single sample
  • Differential splicing analysis (exploratory):
    • Fix crash when inputting non-numeric values or minimum larger than the maximum limit as the axes for the splicing scatter plot