1.4.1

• GTEx data loading:
  • Add input elements to allow GTEx gene expression loading in the graphical interface
  • Fix bug that did not allow to select tissues to load GTEx v7 data (graphical interface)
  • Fix splicing events not being quantified based on GTEx v7 junction reads
• Gene expression normalisation:
  • Fix misleading gene expression (non-)normalisation by converting reads to counts per million (CPM) using edgeR::cpm after normalisation using edgeR::calcNormFactor
• Alternative splicing quantification:
  • Updated support to properly parse new notation of alternative splicing annotation from Bioconductor (backwards compatible with older notation)
  • Raise error when no splicing events after quantification
  • Fix warning following the quantification of splicing events or its loading (incorrect parsing of gene information from splicing events)
• Dimensionality reduction:
  • Use the number (instead of the percentage) of tolerated missing values per sample as the argument to impute data from the remaining samples for those values before performing dimensionality reduction; by default, missing values are tolerated for 10 samples
• Update file description and README
• Minor bug fixes and improvements