MutAnt

Current code contains code to convert dbNSFP database into suitable for MutAnt format

Usage

Download the latest dbNSFP release from the official site. We recommend to use softgenetics ftp link.

wget ftp://dbnsfp:dbnsfp@dbnsfp.softgenetics.com/dbNSFP4.6a.zip

Unzip the downloaded folder with any suitable program and locate into folder. For example:

unzip dbNSFP4.6a.zip && cd dbNSFP4.6a

Copy file suitable for chosen genome version, hg38 or hg19 into folder with dbNSFP database. From the folder run:

cp ~/MutAnt/generate_aggregated_database_hg38.sh .

Edit dbNSFP version in the downloaded file, default version is set to 4.6a. For, example, open file with nano and change version in line 3: version="4.6a"

Launch the conversion script

sh generate_aggregated_database_hg38.sh