MHASpread is a multi-host, single-pathogen, coupled multiscale model designed to simulate epidemic trajectories of diseases. It incorporates various customizable control actions specific to different zones (such as infected, buffer, and surveillance zones), including depopulation, vaccination, and animal movement standstills, among other countermeasures. The model relies on two main sources of data: population and events. For a detailed description of the data format, please refer to data_format.md. An example of R Script about how to run is presented here.
Example of stochastic dynamics of a farm with 100 animals:
Infected farms over time, considering different host species:
Number of infected animals for all host species (the susceptible compartment is excluded to improve data visualization):
Evaluate the performance of the simulated control actions:
This model source is provided under the Proprietary License.
AUTHOR=Cardenas Nicolas C. , Lopes Francisco P. N. , Machado Alencar , Maran Vinicius , Trois Celio , Machado Felipe Amadori , Machado Gustavo TITLE=Modeling foot-and-mouth disease dissemination in Rio Grande do Sul, Brazil and evaluating the effectiveness of control measures JOURNAL=Frontiers in Veterinary Science VOLUME=11 YEAR=2024 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1468864 DOI=10.3389/fvets.2024.1468864 ISSN=2297-1769
Publisehd article is available here.
This model is funded by FUNDESA RS.
💻 Nicolas Cardenas 
💻 LUMAC team at Universidade Federal de Santa Maria
