diff --git a/drivers/vdpa/vdpa_user/vduse_dev.c b/drivers/vdpa/vdpa_user/vduse_dev.c
index 5f5c21674fdce5..0d84e6a9c3cca1 100644
--- a/drivers/vdpa/vdpa_user/vduse_dev.c
+++ b/drivers/vdpa/vdpa_user/vduse_dev.c
@@ -726,7 +726,11 @@ static int vduse_vdpa_set_vq_affinity(struct vdpa_device *vdpa, u16 idx,
 {
 	struct vduse_dev *dev = vdpa_to_vduse(vdpa);
 
-	cpumask_copy(&dev->vqs[idx]->irq_affinity, cpu_mask);
+	if (cpu_mask)
+		cpumask_copy(&dev->vqs[idx]->irq_affinity, cpu_mask);
+	else
+		cpumask_setall(&dev->vqs[idx]->irq_affinity);
+
 	return 0;
 }