diff --git a/superset/viz.py b/superset/viz.py
index 786fad11da942..bb67308b96285 100644
--- a/superset/viz.py
+++ b/superset/viz.py
@@ -1224,7 +1224,9 @@ def get_data(self, df):
         comparison_type = fd.get('comparison_type') or 'values'
         df = self.process_data(df)
         if comparison_type == 'values':
-            chart_data = self.to_series(df)
+            # Filter out series with all NaN
+            chart_data = self.to_series(df.dropna(axis=1, how='all'))
+
             for i, (label, df2) in enumerate(self._extra_chart_data):
                 chart_data.extend(
                     self.to_series(