diff --git a/docs/reference-guides/data/data-core-editor.md b/docs/reference-guides/data/data-core-editor.md
index e1e212e1019d1..b1d767284611f 100644
--- a/docs/reference-guides/data/data-core-editor.md
+++ b/docs/reference-guides/data/data-core-editor.md
@@ -968,10 +968,6 @@ _Returns_
 Returns whether the pre-publish panel should be shown
 or skipped when the user clicks the "publish" button.
 
-_Parameters_
-
--   _state_ `Object`: Global application state.
-
 _Returns_
 
 -   `boolean`: Whether the pre-publish panel should be shown or not.
@@ -1049,11 +1045,7 @@ Action that creates an undo history record.
 
 ### disablePublishSidebar
 
-Action that disables the publish sidebar.
-
-_Returns_
-
--   `Object`: Action object
+Disables the publish sidebar.
 
 ### editPost
 
@@ -1067,11 +1059,7 @@ _Parameters_
 
 ### enablePublishSidebar
 
-Action that enables the publish sidebar.
-
-_Returns_
-
--   `Object`: Action object
+Enable the publish sidebar.
 
 ### enterFormattedText
 
diff --git a/package-lock.json b/package-lock.json
index 245a22583d7a8..a7039a2d554ad 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -17688,6 +17688,7 @@
 				"@wordpress/keycodes": "file:packages/keycodes",
 				"@wordpress/media-utils": "file:packages/media-utils",
 				"@wordpress/notices": "file:packages/notices",
+				"@wordpress/preferences": "file:packages/preferences",
 				"@wordpress/reusable-blocks": "file:packages/reusable-blocks",
 				"@wordpress/rich-text": "file:packages/rich-text",
 				"@wordpress/server-side-render": "file:packages/server-side-render",
diff --git a/packages/data/src/plugins/persistence/index.js b/packages/data/src/plugins/persistence/index.js
index 89f73737cc59a..f00f8a8fc2b18 100644
--- a/packages/data/src/plugins/persistence/index.js
+++ b/packages/data/src/plugins/persistence/index.js
@@ -300,9 +300,19 @@ export function migrateFeaturePreferencesToPreferencesStore(
 	}
 }
 
+/**
+ * Migrates an individual item inside the `preferences` object for a store.
+ *
+ * @param {Object}    persistence   The persistence interface.
+ * @param {Object}    migrate       An options object that contains details of the migration.
+ * @param {string}    migrate.from  The name of the store to migrate from.
+ * @param {string}    migrate.scope The scope in the preferences store to migrate to.
+ * @param {string}    key           The key in the preferences object to migrate.
+ * @param {?Function} convert       A function that converts preferences from one format to another.
+ */
 export function migrateIndividualPreferenceToPreferencesStore(
 	persistence,
-	sourceStoreName,
+	{ from: sourceStoreName, scope },
 	key,
 	convert = identity
 ) {
@@ -311,14 +321,12 @@ export function migrateIndividualPreferenceToPreferencesStore(
 	const sourcePreference = state[ sourceStoreName ]?.preferences?.[ key ];
 
 	// There's nothing to migrate, exit early.
-	if ( ! sourcePreference ) {
+	if ( sourcePreference === undefined ) {
 		return;
 	}
 
 	const targetPreference =
-		state[ preferencesStoreName ]?.preferences?.[ sourceStoreName ]?.[
-			key
-		];
+		state[ preferencesStoreName ]?.preferences?.[ scope ]?.[ key ];
 
 	// There's existing data at the target, so don't overwrite it, exit early.
 	if ( targetPreference ) {
@@ -327,7 +335,7 @@ export function migrateIndividualPreferenceToPreferencesStore(
 
 	const otherScopes = state[ preferencesStoreName ]?.preferences;
 	const otherPreferences =
-		state[ preferencesStoreName ]?.preferences?.[ sourceStoreName ];
+		state[ preferencesStoreName ]?.preferences?.[ scope ];
 
 	// Pass an object with the key and value as this allows the convert
 	// function to convert to a data structure that has different keys.
@@ -336,7 +344,7 @@ export function migrateIndividualPreferenceToPreferencesStore(
 	persistence.set( preferencesStoreName, {
 		preferences: {
 			...otherScopes,
-			[ sourceStoreName ]: {
+			[ scope ]: {
 				...otherPreferences,
 				...convertedPreferences,
 			},
@@ -602,28 +610,33 @@ persistencePlugin.__unstableMigrate = ( pluginOptions ) => {
 	// Other ad-hoc preferences.
 	migrateIndividualPreferenceToPreferencesStore(
 		persistence,
-		'core/edit-post',
+		{ from: 'core/edit-post', scope: 'core/edit-post' },
 		'hiddenBlockTypes'
 	);
 	migrateIndividualPreferenceToPreferencesStore(
 		persistence,
-		'core/edit-post',
+		{ from: 'core/edit-post', scope: 'core/edit-post' },
 		'editorMode'
 	);
 	migrateIndividualPreferenceToPreferencesStore(
 		persistence,
-		'core/edit-post',
+		{ from: 'core/edit-post', scope: 'core/edit-post' },
 		'preferredStyleVariations'
 	);
 	migrateIndividualPreferenceToPreferencesStore(
 		persistence,
-		'core/edit-post',
+		{ from: 'core/edit-post', scope: 'core/edit-post' },
 		'panels',
 		convertEditPostPanels
 	);
 	migrateIndividualPreferenceToPreferencesStore(
 		persistence,
-		'core/edit-site',
+		{ from: 'core/editor', scope: 'core/edit-post' },
+		'isPublishSidebarEnabled'
+	);
+	migrateIndividualPreferenceToPreferencesStore(
+		persistence,
+		{ from: 'core/edit-site', scope: 'core/edit-site' },
 		'editorMode'
 	);
 	migrateInterfaceEnableItemsToPreferencesStore( persistence );
diff --git a/packages/data/src/plugins/persistence/test/index.js b/packages/data/src/plugins/persistence/test/index.js
index 0b2c7e9e3643d..9e442a63daa7e 100644
--- a/packages/data/src/plugins/persistence/test/index.js
+++ b/packages/data/src/plugins/persistence/test/index.js
@@ -694,7 +694,7 @@ describe( 'migrateIndividualPreferenceToPreferencesStore', () => {
 
 		migrateIndividualPreferenceToPreferencesStore(
 			persistenceInterface,
-			'core/test',
+			{ from: 'core/test', scope: 'core/test' },
 			'myPreference'
 		);
 
@@ -743,7 +743,7 @@ describe( 'migrateIndividualPreferenceToPreferencesStore', () => {
 
 		migrateIndividualPreferenceToPreferencesStore(
 			persistenceInterface,
-			'core/test',
+			{ from: 'core/test', scope: 'core/test' },
 			'myPreference'
 		);
 
@@ -771,6 +771,41 @@ describe( 'migrateIndividualPreferenceToPreferencesStore', () => {
 		} );
 	} );
 
+	it( 'supports moving data to a scope that is differently named to the source store', () => {
+		const persistenceInterface = createPersistenceInterface( {
+			storageKey: 'test-username',
+		} );
+
+		const initialState = {
+			preferences: {
+				myPreference: '123',
+			},
+		};
+
+		persistenceInterface.set( 'core/source', initialState );
+
+		migrateIndividualPreferenceToPreferencesStore(
+			persistenceInterface,
+			{ from: 'core/source', scope: 'core/destination' },
+			'myPreference'
+		);
+
+		expect( persistenceInterface.get() ).toEqual( {
+			'core/preferences': {
+				preferences: {
+					'core/destination': {
+						myPreference: '123',
+					},
+				},
+			},
+			'core/source': {
+				preferences: {
+					myPreference: undefined,
+				},
+			},
+		} );
+	} );
+
 	it( 'does not migrate data if there is already a matching preference key at the target', () => {
 		const persistenceInterface = createPersistenceInterface( {
 			storageKey: 'test-username',
@@ -792,7 +827,7 @@ describe( 'migrateIndividualPreferenceToPreferencesStore', () => {
 
 		migrateIndividualPreferenceToPreferencesStore(
 			persistenceInterface,
-			'core/test',
+			{ from: 'core/test', scope: 'core/test' },
 			'myPreference'
 		);
 
@@ -811,6 +846,37 @@ describe( 'migrateIndividualPreferenceToPreferencesStore', () => {
 			},
 		} );
 	} );
+
+	it( 'migrates preferences that have a `false` value', () => {
+		const persistenceInterface = createPersistenceInterface( {
+			storageKey: 'test-username',
+		} );
+
+		persistenceInterface.set( 'core/test', {
+			preferences: {
+				myFalsePreference: false,
+			},
+		} );
+
+		migrateIndividualPreferenceToPreferencesStore(
+			persistenceInterface,
+			{ from: 'core/test', scope: 'core/test' },
+			'myFalsePreference'
+		);
+
+		expect( persistenceInterface.get() ).toEqual( {
+			'core/preferences': {
+				preferences: {
+					'core/test': {
+						myFalsePreference: false,
+					},
+				},
+			},
+			'core/test': {
+				preferences: {},
+			},
+		} );
+	} );
 } );
 
 describe( 'migrateThirdPartyFeaturePreferencesToPreferencesStore', () => {
diff --git a/packages/edit-post/src/index.js b/packages/edit-post/src/index.js
index 3d3901f10a731..6ff6a7603d89f 100644
--- a/packages/edit-post/src/index.js
+++ b/packages/edit-post/src/index.js
@@ -112,6 +112,7 @@ export function initializeEditor(
 		fullscreenMode: true,
 		hiddenBlockTypes: [],
 		inactivePanels: [],
+		isPublishSidebarEnabled: true,
 		openPanels: [ 'post-status' ],
 		preferredStyleVariations: {},
 		showBlockBreadcrumbs: true,
diff --git a/packages/edit-post/src/index.native.js b/packages/edit-post/src/index.native.js
index 48738bd68d8a7..b825d50ace0c0 100644
--- a/packages/edit-post/src/index.native.js
+++ b/packages/edit-post/src/index.native.js
@@ -27,6 +27,7 @@ export function initializeEditor( id, postType, postId ) {
 		fullscreenMode: true,
 		hiddenBlockTypes: [],
 		inactivePanels: [],
+		isPublishSidebarEnabled: true,
 		openPanels: [ 'post-status' ],
 		preferredStyleVariations: {},
 		welcomeGuide: true,
diff --git a/packages/editor/package.json b/packages/editor/package.json
index 14dcdc1f2c0fa..a2f0798fcba20 100644
--- a/packages/editor/package.json
+++ b/packages/editor/package.json
@@ -50,6 +50,7 @@
 		"@wordpress/keycodes": "file:../keycodes",
 		"@wordpress/media-utils": "file:../media-utils",
 		"@wordpress/notices": "file:../notices",
+		"@wordpress/preferences": "file:../preferences",
 		"@wordpress/reusable-blocks": "file:../reusable-blocks",
 		"@wordpress/rich-text": "file:../rich-text",
 		"@wordpress/server-side-render": "file:../server-side-render",
diff --git a/packages/editor/src/store/actions.js b/packages/editor/src/store/actions.js
index 02aceef3eaf9a..03e0a51186d9b 100644
--- a/packages/editor/src/store/actions.js
+++ b/packages/editor/src/store/actions.js
@@ -16,6 +16,7 @@ import {
 import { store as noticesStore } from '@wordpress/notices';
 import { store as coreStore } from '@wordpress/core-data';
 import { store as blockEditorStore } from '@wordpress/block-editor';
+import { store as preferencesStore } from '@wordpress/preferences';
 
 /**
  * Internal dependencies
@@ -320,26 +321,22 @@ export function updatePostLock( lock ) {
 }
 
 /**
- * Action that enables the publish sidebar.
- *
- * @return {Object} Action object
+ * Enable the publish sidebar.
  */
-export function enablePublishSidebar() {
-	return {
-		type: 'ENABLE_PUBLISH_SIDEBAR',
-	};
-}
+export const enablePublishSidebar = () => ( { registry } ) => {
+	registry
+		.dispatch( preferencesStore )
+		.set( 'core/edit-post', 'isPublishSidebarEnabled', true );
+};
 
 /**
- * Action that disables the publish sidebar.
- *
- * @return {Object} Action object
+ * Disables the publish sidebar.
  */
-export function disablePublishSidebar() {
-	return {
-		type: 'DISABLE_PUBLISH_SIDEBAR',
-	};
-}
+export const disablePublishSidebar = () => ( { registry } ) => {
+	registry
+		.dispatch( preferencesStore )
+		.set( 'core/edit-post', 'isPublishSidebarEnabled', false );
+};
 
 /**
  * Action that locks post saving.
diff --git a/packages/editor/src/store/defaults.js b/packages/editor/src/store/defaults.js
index a626bd7345693..66bcdc72dd8be 100644
--- a/packages/editor/src/store/defaults.js
+++ b/packages/editor/src/store/defaults.js
@@ -3,11 +3,6 @@
  */
 import { SETTINGS_DEFAULTS } from '@wordpress/block-editor';
 
-export const PREFERENCES_DEFAULTS = {
-	insertUsage: {}, // Should be kept for backward compatibility, see: https://github.com/WordPress/gutenberg/issues/14580.
-	isPublishSidebarEnabled: true,
-};
-
 /**
  * The default post editor settings.
  *
diff --git a/packages/editor/src/store/index.js b/packages/editor/src/store/index.js
index a9a3ec8cfdada..baee4d9197d0c 100644
--- a/packages/editor/src/store/index.js
+++ b/packages/editor/src/store/index.js
@@ -1,7 +1,7 @@
 /**
  * WordPress dependencies
  */
-import { createReduxStore, registerStore } from '@wordpress/data';
+import { createReduxStore, register } from '@wordpress/data';
 
 /**
  * Internal dependencies
@@ -33,12 +33,6 @@ export const storeConfig = {
  */
 export const store = createReduxStore( STORE_NAME, {
 	...storeConfig,
-	persist: [ 'preferences' ],
 } );
 
-// Once we build a more generic persistence plugin that works across types of stores
-// we'd be able to replace this with a register call.
-registerStore( STORE_NAME, {
-	...storeConfig,
-	persist: [ 'preferences' ],
-} );
+register( store );
diff --git a/packages/editor/src/store/reducer.js b/packages/editor/src/store/reducer.js
index fc5be10508bd4..7567c4189254a 100644
--- a/packages/editor/src/store/reducer.js
+++ b/packages/editor/src/store/reducer.js
@@ -11,7 +11,7 @@ import { combineReducers } from '@wordpress/data';
 /**
  * Internal dependencies
  */
-import { PREFERENCES_DEFAULTS, EDITOR_SETTINGS_DEFAULTS } from './defaults';
+import { EDITOR_SETTINGS_DEFAULTS } from './defaults';
 
 /**
  * Returns a post attribute value, flattening nested rendered content using its
@@ -119,32 +119,6 @@ export function template( state = { isValid: true }, action ) {
 	return state;
 }
 
-/**
- * Reducer returning the user preferences.
- *
- * @param {Object} state  Current state.
- * @param {Object} action Dispatched action.
- *
- * @return {string} Updated state.
- */
-export function preferences( state = PREFERENCES_DEFAULTS, action ) {
-	switch ( action.type ) {
-		case 'ENABLE_PUBLISH_SIDEBAR':
-			return {
-				...state,
-				isPublishSidebarEnabled: true,
-			};
-
-		case 'DISABLE_PUBLISH_SIDEBAR':
-			return {
-				...state,
-				isPublishSidebarEnabled: false,
-			};
-	}
-
-	return state;
-}
-
 /**
  * Reducer returning current network request state (whether a request to
  * the WP REST API is in progress, successful, or failed).
@@ -282,7 +256,6 @@ export function editorSettings( state = EDITOR_SETTINGS_DEFAULTS, action ) {
 export default combineReducers( {
 	postId,
 	postType,
-	preferences,
 	saving,
 	postLock,
 	template,
diff --git a/packages/editor/src/store/reducer.native.js b/packages/editor/src/store/reducer.native.js
index b3d7e8e435b5a..991addd88620b 100644
--- a/packages/editor/src/store/reducer.native.js
+++ b/packages/editor/src/store/reducer.native.js
@@ -9,7 +9,6 @@ import { combineReducers } from '@wordpress/data';
 import {
 	postId,
 	postType,
-	preferences,
 	saving,
 	postLock,
 	postSavingLock,
@@ -84,7 +83,6 @@ export default combineReducers( {
 	postId,
 	postType,
 	postTitle,
-	preferences,
 	saving,
 	postLock,
 	postSavingLock,
diff --git a/packages/editor/src/store/selectors.js b/packages/editor/src/store/selectors.js
index db452ecf23130..8915197dc2932 100644
--- a/packages/editor/src/store/selectors.js
+++ b/packages/editor/src/store/selectors.js
@@ -20,11 +20,11 @@ import { Platform } from '@wordpress/element';
 import { layout } from '@wordpress/icons';
 import { store as blockEditorStore } from '@wordpress/block-editor';
 import { store as coreStore } from '@wordpress/core-data';
+import { store as preferencesStore } from '@wordpress/preferences';
 
 /**
  * Internal dependencies
  */
-import { PREFERENCES_DEFAULTS } from './defaults';
 import {
 	EDIT_MERGE_PROPERTIES,
 	PERMALINK_POSTNAME_REGEX,
@@ -1093,16 +1093,15 @@ export function canUserUseUnfilteredHTML( state ) {
  * Returns whether the pre-publish panel should be shown
  * or skipped when the user clicks the "publish" button.
  *
- * @param {Object} state Global application state.
- *
  * @return {boolean} Whether the pre-publish panel should be shown or not.
  */
-export function isPublishSidebarEnabled( state ) {
-	if ( state.preferences.hasOwnProperty( 'isPublishSidebarEnabled' ) ) {
-		return state.preferences.isPublishSidebarEnabled;
-	}
-	return PREFERENCES_DEFAULTS.isPublishSidebarEnabled;
-}
+export const isPublishSidebarEnabled = createRegistrySelector(
+	( select ) => () =>
+		!! select( preferencesStore ).get(
+			'core/edit-post',
+			'isPublishSidebarEnabled'
+		)
+);
 
 /**
  * Return the current block list.
diff --git a/packages/editor/src/store/test/actions.js b/packages/editor/src/store/test/actions.js
index 7f2357964404f..ee223c09f3965 100644
--- a/packages/editor/src/store/test/actions.js
+++ b/packages/editor/src/store/test/actions.js
@@ -6,6 +6,7 @@ import { store as blockEditorStore } from '@wordpress/block-editor';
 import { store as coreStore } from '@wordpress/core-data';
 import { createRegistry } from '@wordpress/data';
 import { store as noticesStore } from '@wordpress/notices';
+import { store as preferencesStore } from '@wordpress/preferences';
 
 /**
  * Internal dependencies
@@ -46,6 +47,7 @@ function createRegistryWithStores() {
 	registry.register( coreStore );
 	registry.register( editorStore );
 	registry.register( noticesStore );
+	registry.register( preferencesStore );
 
 	// Register post type entity.
 	registry.dispatch( coreStore ).addEntities( [ postTypeConfig ] );
@@ -349,4 +351,39 @@ describe( 'Editor actions', () => {
 			} );
 		} );
 	} );
+
+	describe( 'enablePublishSidebar', () => {
+		it( 'enables the publish sidebar', () => {
+			const registry = createRegistryWithStores();
+
+			// Starts off as `undefined` as a default hasn't been set.
+			expect(
+				registry.select( editorStore ).isPublishSidebarEnabled()
+			).toBe( false );
+
+			registry.dispatch( editorStore ).enablePublishSidebar();
+
+			expect(
+				registry.select( editorStore ).isPublishSidebarEnabled()
+			).toBe( true );
+		} );
+	} );
+
+	describe( 'disablePublishSidebar', () => {
+		it( 'disables the publish sidebar', () => {
+			const registry = createRegistryWithStores();
+
+			// Enable it to start with so that can test it flipping from `true` to `false`.
+			registry.dispatch( editorStore ).enablePublishSidebar();
+			expect(
+				registry.select( editorStore ).isPublishSidebarEnabled()
+			).toBe( true );
+
+			registry.dispatch( editorStore ).disablePublishSidebar();
+
+			expect(
+				registry.select( editorStore ).isPublishSidebarEnabled()
+			).toBe( false );
+		} );
+	} );
 } );
diff --git a/packages/editor/src/store/test/reducer.js b/packages/editor/src/store/test/reducer.js
index d06b90dd672fe..3b0ea9d3340a1 100644
--- a/packages/editor/src/store/test/reducer.js
+++ b/packages/editor/src/store/test/reducer.js
@@ -11,7 +11,6 @@ import {
 	isUpdatingSamePostProperty,
 	shouldOverwriteState,
 	getPostRawValue,
-	preferences,
 	saving,
 	postSavingLock,
 	postAutosavingLock,
@@ -163,36 +162,6 @@ describe( 'state', () => {
 		} );
 	} );
 
-	describe( 'preferences()', () => {
-		it( 'should apply all defaults', () => {
-			const state = preferences( undefined, {} );
-			expect( state ).toEqual( {
-				insertUsage: {},
-				isPublishSidebarEnabled: true,
-			} );
-		} );
-
-		it( 'should disable the publish sidebar', () => {
-			const original = deepFreeze( preferences( undefined, {} ) );
-			const state = preferences( original, {
-				type: 'DISABLE_PUBLISH_SIDEBAR',
-			} );
-
-			expect( state.isPublishSidebarEnabled ).toBe( false );
-		} );
-
-		it( 'should enable the publish sidebar', () => {
-			const original = deepFreeze(
-				preferences( { isPublishSidebarEnabled: false }, {} )
-			);
-			const state = preferences( original, {
-				type: 'ENABLE_PUBLISH_SIDEBAR',
-			} );
-
-			expect( state.isPublishSidebarEnabled ).toBe( true );
-		} );
-	} );
-
 	describe( 'saving()', () => {
 		it( 'should update when a request is started', () => {
 			const state = saving( null, {
diff --git a/packages/editor/src/store/test/selectors.js b/packages/editor/src/store/test/selectors.js
index 3bbdc27e6e352..ef0ba07e720c6 100644
--- a/packages/editor/src/store/test/selectors.js
+++ b/packages/editor/src/store/test/selectors.js
@@ -22,7 +22,6 @@ import { layout, footer, header } from '@wordpress/icons';
  * Internal dependencies
  */
 import * as _selectors from '../selectors';
-import { PREFERENCES_DEFAULTS } from '../defaults';
 
 const selectors = { ..._selectors };
 const selectorNames = Object.keys( selectors );
@@ -182,7 +181,6 @@ const {
 	didPostSaveRequestFail,
 	getSuggestedPostFormat,
 	getEditedPostContent,
-	isPublishSidebarEnabled,
 	isPermalinkEditable,
 	getPermalink,
 	getPermalinkParts,
@@ -2570,39 +2568,6 @@ describe( 'selectors', () => {
 		} );
 	} );
 
-	describe( 'isPublishSidebarEnabled', () => {
-		it( 'should return the value on state if it is thruthy', () => {
-			const state = {
-				preferences: {
-					isPublishSidebarEnabled: true,
-				},
-			};
-			expect( isPublishSidebarEnabled( state ) ).toBe(
-				state.preferences.isPublishSidebarEnabled
-			);
-		} );
-
-		it( 'should return the value on state if it is falsy', () => {
-			const state = {
-				preferences: {
-					isPublishSidebarEnabled: false,
-				},
-			};
-			expect( isPublishSidebarEnabled( state ) ).toBe(
-				state.preferences.isPublishSidebarEnabled
-			);
-		} );
-
-		it( 'should return the default value if there is no isPublishSidebarEnabled key on state', () => {
-			const state = {
-				preferences: {},
-			};
-			expect( isPublishSidebarEnabled( state ) ).toBe(
-				PREFERENCES_DEFAULTS.isPublishSidebarEnabled
-			);
-		} );
-	} );
-
 	describe( 'isPermalinkEditable', () => {
 		it( 'should be false if there is no permalink', () => {
 			const state = {