From 2ec04111cbe78651fc44e82edbd815881579f389 Mon Sep 17 00:00:00 2001
From: "dependabot[bot]" <49699333+dependabot[bot]@users.noreply.github.com>
Date: Tue, 8 Jun 2021 22:38:34 +0000
Subject: [PATCH] Upgrade: Bump pillow from 8.1.1 to 8.2.0

Bumps [pillow](https://github.com/python-pillow/Pillow) from 8.1.1 to 8.2.0.
- [Release notes](https://github.com/python-pillow/Pillow/releases)
- [Changelog](https://github.com/python-pillow/Pillow/blob/master/CHANGES.rst)
- [Commits](https://github.com/python-pillow/Pillow/compare/8.1.1...8.2.0)

---
updated-dependencies:
- dependency-name: pillow
  dependency-type: indirect
...

Signed-off-by: dependabot[bot] <support@github.com>
---
 Pipfile.lock     | 1013 +++++++++++++++++++++++-----------------------
 requirements.txt |   43 +-
 2 files changed, 524 insertions(+), 532 deletions(-)

diff --git a/Pipfile.lock b/Pipfile.lock
index 20ece82..ed36b2d 100644
--- a/Pipfile.lock
+++ b/Pipfile.lock
@@ -31,10 +31,10 @@
         },
         "attrs": {
             "hashes": [
-                "sha256:31b2eced602aa8423c2aea9c76a724617ed67cf9513173fd3a4f03e3a929c7e6",
-                "sha256:832aa3cde19744e49938b91fea06d69ecb9e649c93ba974535d08ad92164f700"
+                "sha256:149e90d6d8ac20db7a955ad60cf0e6881a3f20d37096140088356da6c716b0b1",
+                "sha256:ef6aaac3ca6cd92904cdd0d83f629a15f18053ec84e6432106f7a4d04ae4f5fb"
             ],
-            "version": "==20.3.0"
+            "version": "==21.2.0"
         },
         "backcall": {
             "hashes": [
@@ -52,10 +52,10 @@
         },
         "certifi": {
             "hashes": [
-                "sha256:1a4995114262bffbc2413b159f2a1a480c969de6e6eb13ee966d470af86af59c",
-                "sha256:719a74fb9e33b9bd44cc7f3a8d94bc35e4049deebe19ba7d8e108280cfd59830"
+                "sha256:2bbf76fd432960138b3ef6dda3dde0544f27cbf8546c458e60baf371917ba9ee",
+                "sha256:50b1e4f8446b06f41be7dd6338db18e0990601dce795c2b1686458aa7e8fa7d8"
             ],
-            "version": "==2020.12.5"
+            "version": "==2021.5.30"
         },
         "chardet": {
             "hashes": [
@@ -81,46 +81,50 @@
         },
         "cython": {
             "hashes": [
-                "sha256:105d813eedf276588a02a240ece2f7bca8235aee9bb48e25293410c3c1ac7230",
-                "sha256:15b2ba47858d7949a036d4ba6e838120bf3c06983769e99d12867a2c8cd0cd91",
-                "sha256:182e78d75515e3d50f31cfde501fbf2af7ee0698e8149f41048db5d3c98ffc8f",
-                "sha256:3ce10572a6b7fd5baa755f11cdf09830ae518e6f837aa38c31ec534b1f874fd4",
-                "sha256:40a87c9ecd0b1b485804c70b16427e88bd07bff9f270d022d872869ff4d6ac6e",
-                "sha256:59c950513c485f1e8da0e04a2a91f71508c5e98b6912ce66588c6aee72d8e4d1",
-                "sha256:5cc5e72a106d7abc12b6e58883c914bce0b2031df6035014094a15593052db12",
-                "sha256:6609babc68d37bb92a1b85ebd867405f720aeb2a6af946f6bd7f71b22dbb91cf",
-                "sha256:667b169c89c4b8eb79d35822508ed8d77b9421af085142fad20bfef775a295d2",
-                "sha256:7265abb33f154663a052c47213b978ec703f89a938bca38f425f25d4e8ba2211",
-                "sha256:761b965b5abcea072ba642dbb740e44532bc88618f34b605c05de1d6088b1cdd",
-                "sha256:88bebb8803adac0b64426fd261752925e8bf301b1986078e9506670bcbb5307f",
-                "sha256:92c028e0d4ac9e32b2cf6c970f7f6c5c3aaa87f011798201ef56746705a8f01a",
-                "sha256:97511722515b66851d3f77d64b1970a97e5114c4007efd5a0a307936e156a24c",
-                "sha256:a6f5bf7fece95dd62ba13a9edb7d3ecc1a9097e6f0fde78c5fad763163157472",
-                "sha256:a8aee32da407f215652959fc6568277cfd35a24714a5238c8a9778bf34d91ace",
-                "sha256:ab4c34d8693a62f1b8261a131784a3db397ceaa03ea90a5799574623acaa2c2c",
-                "sha256:af646d37e23fc3ba217c587096fac4e57006d8173d2a2365763287071e0eec2d",
-                "sha256:b53c9d7b545c70f462408000affdd330cb87d05f83a58a9ccd72d19c8df80d56",
-                "sha256:ba7f34e07ca0d1ce4ba8d9e3da6d2eb0b1ac6cb9896d2c821b28a9ac9504bcfe",
-                "sha256:bbc48be45ee9eba2d0268bf616220cfb46d998ad85524f3cf752d55eb6dd3379",
-                "sha256:c4f2c8cceffd8403468b542570826174564fe2c6549dd199a75c13720add4981",
-                "sha256:d73a4851d1dbdcc70e619ccb104877d5e523d0fc5aef6fb6fbba4344c1f60cae",
-                "sha256:d76feb00f754d86e6d48f39b59a4e9a8fcfed1e6e3e433d18e3677ff19ff2911",
-                "sha256:dc42b78b62815abea19a37d186011cca57f72ec509f56fa6c43a71b2e8c6a24f",
-                "sha256:df6b83c7a6d1d967ea89a2903e4a931377634a297459652e4551734c48195406",
-                "sha256:e8c84ad389b3f36433e1be88dd7a1e36db4ab5b4848f5899cbd0a1cdc443b925",
-                "sha256:f5f57b2e13cc3aa95526145ffa551df529f04bf5d137c59350e7accff9362dc0",
-                "sha256:f7064df99094b4fd09c9ebcca6c94a652fac04c7dce514a4f2ab6ce23fcd0ba4",
-                "sha256:f89c19480d137026f04a34cbd54ab0fb328b29005c91d3a36d06b9c4710152c1",
-                "sha256:fedecbd2ad6535e30dd3b43ca9b493a1930d5167257a3fb60687bd425f6fdc54"
-            ],
-            "version": "==0.29.22"
+                "sha256:0c4b9f7e3aa004cf3f364e3e772f55fec5740485bafea99d1f13bdc9bbd8a545",
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+                "sha256:20cb50d9fede8029bdb50875458f07a27f909289aeed4cdb9c19544dd9a9bc45",
+                "sha256:2365f3b5e6451b6bc6dcd262230656f4ade1d862ec2f6c22154deebef37c08b6",
+                "sha256:266459c7e48fe3c6c492b297e4033e42d4c6863cc1a1ff7cc4034949fc574fa6",
+                "sha256:282263628c5d601b313d5920f7b6d7e08c7fedbddacd080c4858aa04d86b6b4b",
+                "sha256:2a3bbce689a2fddb85aa66712d93875c99bf7f64ac82b1d149ecce522a7a4e0c",
+                "sha256:2af52d312e96b38ded38b34d06e22685c226b1b0e58278bd27209f5d2385d115",
+                "sha256:355a6e768d91e21fbf477b61881bab64b7a2da386a166898997bccefd532cf5d",
+                "sha256:37ff66039e3d138ec968ee1d1e12441fa5fb4e6a9c5458bc3c3a232f01be4a7d",
+                "sha256:3b29224eb62309a10819d923dc6262f769e4f3facfee3cd06372c355e5b38b33",
+                "sha256:3ef530f975e3a760e7282fce2a25f900fa63f96d17321b4aa5f5542eb9859cdf",
+                "sha256:41cd0dd2ff5d78466e73409db509887a84449b400074d4f217980cedbb18e4be",
+                "sha256:474c1a29ab43e29d990df279e2cf6aa96baa9208f5cd4bc76ac87ffcdf1e2945",
+                "sha256:4858043ac5f96a8f0277cf63760bb39b9521c1f897678cf1d22423f3e758f4ed",
+                "sha256:4b0bcf2e06a9063fc78c3243ed4003228375d532ef13b9e5d7183be8f0a52cf5",
+                "sha256:4b6824b58d4373224fc76ee8bee6b35c2d17c91a1ed0fa67b88440f63daebe50",
+                "sha256:4d7c3b0882d8757c601eaf288fc0d321d5c7ac6c3afb8c42eddf9325a3419cf5",
+                "sha256:519fccf526d26b377e1db22f22aa44889b28bc5833ec106588cb13557e8ba2da",
+                "sha256:58dc06871bfdb0592542d779714fe9f918e11ba20ac07757dd63b198bdc704fe",
+                "sha256:5a6792153b728a0240e55bbb5b643f4f7e45c76319e03abf15bf367471ea1d1a",
+                "sha256:5be3ae3189cf7d0e9bbeafb854496dc7030c6f6a5602d809435fab8223543a41",
+                "sha256:625a16103770fd92b487b701fb0c07e5790b080f40fa11ce572a2d56d9e9fcca",
+                "sha256:6a0d31452f0245daacb14c979c77e093eb1a546c760816b5eed0047686baad8e",
+                "sha256:794e3df0b57e16bce7583ac909126f4cb381fe566adadb20484d89095855eedb",
+                "sha256:7b7a766726d207d7cd57aff0fcb4b35ce042d3cc88a421fcdb45eeb61a5b9d12",
+                "sha256:7d6a33c8a11f05f698e215bfdb837f32c27f63c20f3af863557ed91c748dc2be",
+                "sha256:a8eed9c82e8fe07b8a8ffbd36018871a17458903fc25c9d015f37b54513a3efd",
+                "sha256:aa3bb0928fb2aa3a8828801eb8b29af2261c199f805ae835467489e2bdd00372",
+                "sha256:b0699f0dc90181f2458fdb8170455e7798a309e18f41379eda7a2dc8c7aadee0",
+                "sha256:c4b82461edbbcf90f19b319006345b77474a2d7514e1476d49a14bbd55d6b797",
+                "sha256:ceccc03b633113ede1f14ad914a6db5c278ce108c8ddb308a5c01c1567d8a02a",
+                "sha256:ef21c51350462160456eb71df31b0869e5141e940f22c61c358bdb6e3ebc3388",
+                "sha256:f4aca6bffb1c1c3c4ada3347d0b162a699c18a66e097ee08b63b3a35118fdfcc",
+                "sha256:ff885f18d169759b57f116d3956e45cd2b9cba989fde348bba091544c668dc11"
+            ],
+            "version": "==0.29.23"
         },
         "decorator": {
             "hashes": [
-                "sha256:41fa54c2a0cc4ba648be4fd43cff00aedf5b9465c9bf18d64325bc225f08f760",
-                "sha256:e3a62f0520172440ca0dcc823749319382e377f37f140a0b99ef45fecb84bfe7"
+                "sha256:6e5c199c16f7a9f0e3a61a4a54b3d27e7dad0dbdde92b944426cb20914376323",
+                "sha256:72ecfba4320a893c53f9706bebb2d55c270c1e51a28789361aa93e4a21319ed5"
             ],
-            "version": "==4.4.2"
+            "version": "==5.0.9"
         },
         "idna": {
             "hashes": [
@@ -131,11 +135,11 @@
         },
         "importlib-metadata": {
             "hashes": [
-                "sha256:742add720a20d0467df2f444ae41704000f50e1234f46174b51f9c6031a1bd71",
-                "sha256:b74159469b464a99cb8cc3e21973e4d96e05d3024d337313fedb618a6e86e6f4"
+                "sha256:833b26fb89d5de469b24a390e9df088d4e52e4ba33b01dc5e0e4f41b81a16c00",
+                "sha256:b142cc1dd1342f31ff04bb7d022492b09920cb64fed867cd3ea6f80fe3ebd139"
             ],
             "markers": "python_version < '3.8'",
-            "version": "==3.7.3"
+            "version": "==4.5.0"
         },
         "iniconfig": {
             "hashes": [
@@ -146,10 +150,10 @@
         },
         "ipykernel": {
             "hashes": [
-                "sha256:98321abefdf0505fb3dc7601f60fc4087364d394bd8fad53107eb1adee9ff475",
-                "sha256:efd07253b54d84d26e0878d268c8c3a41582a18750da633c2febfd2ece0d467d"
+                "sha256:29eee66548ee7c2edb7941de60c0ccf0a7a8dd957341db0a49c5e8e6a0fcb712",
+                "sha256:e976751336b51082a89fc2099fb7f96ef20f535837c398df6eab1283c2070884"
             ],
-            "version": "==5.5.0"
+            "version": "==5.5.5"
         },
         "ipython": {
             "hashes": [
@@ -174,17 +178,17 @@
         },
         "jinja2": {
             "hashes": [
-                "sha256:03e47ad063331dd6a3f04a43eddca8a966a26ba0c5b7207a9a9e4e08f1b29419",
-                "sha256:a6d58433de0ae800347cab1fa3043cebbabe8baa9d29e668f1c768cb87a333c6"
+                "sha256:1f06f2da51e7b56b8f238affdd6b4e2c61e39598a378cc49345bc1bd42a978a4",
+                "sha256:703f484b47a6af502e743c9122595cc812b0271f661722403114f71a79d0f5a4"
             ],
-            "version": "==2.11.3"
+            "version": "==3.0.1"
         },
         "jupyter-client": {
             "hashes": [
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-                "sha256:e053a2c44b6fa597feebe2b3ecb5eea3e03d1d91cc94351a52931ee1426aecfc"
+                "sha256:9715152067e3f7ea3b56f341c9a0f9715c8c7cc316ee0eb13c3c84f5ca0065f5",
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-            "version": "==6.1.12"
+            "version": "==6.2.0"
         },
         "jupyter-core": {
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@@ -249,60 +253,42 @@
         },
         "markupsafe": {
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-            "version": "==1.1.1"
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@@ -334,6 +320,13 @@
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@@ -411,10 +404,10 @@
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@@ -450,42 +443,43 @@
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@@ -503,10 +497,10 @@
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@@ -524,10 +518,10 @@
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@@ -538,10 +532,10 @@
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@@ -552,70 +546,71 @@
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+                "sha256:f995378113cf1b0ccb49386427ea83cb695a5da699960b3569c8a95663a76713"
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+            ],
+            "version": "==1.1.4"
         },
         "python-libsbml": {
             "hashes": [
@@ -654,37 +649,37 @@
         },
         "python-libsedml": {
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         },
         "pytz": {
             "hashes": [
@@ -695,40 +690,40 @@
         },
         "pyzmq": {
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         "requests": {
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@@ -798,10 +793,10 @@
         },
         "six": {
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-            "version": "==1.15.0"
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@@ -872,19 +867,19 @@
         },
         "typing-extensions": {
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-            "version": "==3.7.4.3"
+            "version": "==3.10.0.0"
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-            "version": "==1.26.4"
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@@ -914,16 +909,20 @@
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                 "sha256:7d455c802727710e9dfa69b74ccaab04568386ca17b0ad36350b622cd34606fe",
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                 "sha256:b160416adc0f012fb1f12588a5e6954889510f82f698e23ed4f4fa57f12a0647",
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@@ -948,10 +947,10 @@
         },
         "attrs": {
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@@ -978,14 +977,23 @@
         "cffi": {
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                 "sha256:005a36f41773e148deac64b08f233873a4d0c18b053d37da83f6af4d9087b813",
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@@ -993,6 +1001,7 @@
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@@ -1010,8 +1019,10 @@
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                 "sha256:cbde590d4faaa07c72bf979734738f328d239913ba3e043b1e98fe9a39f8b2b6",
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@@ -1019,10 +1030,10 @@
         },
         "cfgv": {
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-                "sha256:cf22deb93d4bcf92f345a5c3cd39d3d41d6340adc60c78bbbd6588c384fda6a1"
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+            "version": "==3.3.0"
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@@ -1034,10 +1045,10 @@
         },
         "decorator": {
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-                "sha256:e3a62f0520172440ca0dcc823749319382e377f37f140a0b99ef45fecb84bfe7"
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+            "version": "==5.0.9"
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@@ -1048,10 +1059,10 @@
         },
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-                "sha256:edf6116872c863e1aa9d5bb7cb5e05a022c519a4594dc703843343a9ddd9bff1"
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+            "version": "==0.3.2"
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@@ -1077,33 +1088,33 @@
         },
         "identify": {
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-                "sha256:f516f69e62df018a3965a835dccfb3397ed02ddaf513584633c9acaf084be3f2"
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-                "sha256:b74159469b464a99cb8cc3e21973e4d96e05d3024d337313fedb618a6e86e6f4"
+                "sha256:833b26fb89d5de469b24a390e9df088d4e52e4ba33b01dc5e0e4f41b81a16c00",
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-            "version": "==3.7.3"
+            "version": "==4.5.0"
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         "importlib-resources": {
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-                "sha256:ebab3efe74d83b04d6bf5cd9a17f0c5c93e60fb60f30c90f56265fce4682a469"
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-            "version": "==5.1.2"
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-                "sha256:efd07253b54d84d26e0878d268c8c3a41582a18750da633c2febfd2ece0d467d"
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@@ -1128,10 +1139,10 @@
         },
         "isort": {
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-                "sha256:fff4f0c04e1825522ce6949973e83110a6e907750cd92d128b0d14aaaadbffdc"
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+            "version": "==5.8.0"
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         "jedi": {
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@@ -1142,10 +1153,10 @@
         },
         "jinja2": {
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+                "sha256:1f06f2da51e7b56b8f238affdd6b4e2c61e39598a378cc49345bc1bd42a978a4",
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-            "version": "==2.11.3"
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@@ -1165,17 +1176,17 @@
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         "jupyter-client": {
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@@ -1342,10 +1333,10 @@
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@@ -1356,17 +1347,17 @@
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@@ -1383,10 +1374,10 @@
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@@ -1420,17 +1411,17 @@
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-            "version": "==3.0.17"
+            "version": "==3.0.18"
         },
         "ptyprocess": {
             "hashes": [
@@ -1462,10 +1453,10 @@
         },
         "pygments": {
             "hashes": [
-                "sha256:2656e1a6edcdabf4275f9a3640db59fd5de107d88e8663c5d4e9a0fa62f77f94",
-                "sha256:534ef71d539ae97d4c3a4cf7d6f110f214b0e687e92f9cb9d2a3b0d3101289c8"
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+            "version": "==2.9.0"
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         "pylint": {
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@@ -1546,47 +1537,47 @@
         },
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-                "sha256:b62ea18c0458a65ccd5be90f276f7a5a3f26a6dea0066d948ce2fa896051420f",
-                "sha256:c0cde362075ee8f3d2b0353b283e203c2200243b5a15d5c5c03b78112a17e7d4",
-                "sha256:c5e29fe4678f97ce429f076a2a049a3d0b2660ada8f2c621e5dc9939426056dd",
-                "sha256:d18ddc6741b51f3985978f2fda57ddcdae359662d7a6b395bc8ff2292fca14bd",
-                "sha256:da7d4d4c778c86b60949d17531e60c54ed3726878de8a7f8a6d6e7f8cc8c3205",
-                "sha256:f52070871a0fd90a99130babf21f8af192304ec1e995bec2a9533efc21ea4452",
-                "sha256:f5831eff6b125992ec65d973f5151c48003b6754030094723ac4c6e80a97c8c4",
-                "sha256:f7f63ce127980d40f3e6a5fdb87abf17ce1a7c2bd8bf2c7560e1bbce8ab1f92d",
-                "sha256:ff1ea14075bbddd6f29bf6beb8a46d0db779bcec6b9820909584081ec119f8fd"
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-            "version": "==22.0.3"
+                "sha256:089b974ec04d663b8685ac90e86bfe0e4da9d911ff3cf52cb765ff22408b102d",
+                "sha256:0ea7f4237991b0f745a4432c63e888450840bf8cb6c48b93fb7d62864f455529",
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+                "sha256:12ffcf33db6ba7c0e5aaf901e65517f5e2b719367b80bcbfad692f546a297c7a",
+                "sha256:1389b615917d4196962a9b469e947ba862a8ec6f5094a47da5e7a8d404bc07a4",
+                "sha256:18dd2ca4540c476558099891c129e6f94109971d110b549db2a9775c817cedbd",
+                "sha256:24fb5bb641f0b2aa25fc3832f4b6fc62430f14a7d328229fe994b2bcdc07c93a",
+                "sha256:285514956c08c7830da9d94e01f5414661a987831bd9f95e4d89cc8aaae8da10",
+                "sha256:41049cff5265e9cd75606aa2c90a76b9c80b98d8fe70ee08cf4af3cedb113358",
+                "sha256:461ed80d741692d9457ab820b1cc057ba9c37c394e67b647b639f623c8b321f6",
+                "sha256:4b8fb1b3174b56fd020e4b10232b1764e52cf7f3babcfb460c5253bdc48adad0",
+                "sha256:4c4fe69c7dc0d13d4ae180ad650bb900854367f3349d3c16f0569f6c6447f698",
+                "sha256:4e9b9a2f6944acdaf57316436c1acdcb30b8df76726bcf570ad9342bc5001654",
+                "sha256:6355f81947e1fe6e7bb9e123aeb3067264391d3ebe8402709f824ef8673fa6f3",
+                "sha256:68be16107f41563b9f67d93dff1c9f5587e0f76aa8fd91dc04c83d813bcdab1f",
+                "sha256:68e2c4505992ab5b89f976f89a9135742b18d60068f761bef994a6805f1cae0c",
+                "sha256:7040d6dd85ea65703904d023d7f57fab793d7ffee9ba9e14f3b897f34ff2415d",
+                "sha256:734ea6565c71fc2d03d5b8c7d0d7519c96bb5567e0396da1b563c24a4ac66f0c",
+                "sha256:9ee48413a2d3cd867fd836737b4c89c24cea1150a37f4856d82d20293fa7519f",
+                "sha256:a1c77796f395804d6002ff56a6a8168c1f98579896897ad7e35665a9b4a9eec5",
+                "sha256:b2f707b52e09098a7770503e39294ca6e22ae5138ffa1dd36248b6436d23d78e",
+                "sha256:bf80b2cec42d96117248b99d3c86e263a00469c840a778e6cb52d916f4fdf82c",
+                "sha256:c4674004ed64685a38bee222cd75afa769424ec603f9329f0dd4777138337f48",
+                "sha256:c6a81c9e6754465d09a87e3acd74d9bb1f0039b2d785c6899622f0afdb41d760",
+                "sha256:c6d0c32532a0519997e1ded767e184ebb8543bdb351f8eff8570bd461e874efc",
+                "sha256:c8fff75af4c7af92dce9f81fa2a83ed009c3e1f33ee8b5222db2ef80b94e242e",
+                "sha256:cb9f9fe1305ef69b65794655fd89b2209b11bff3e837de981820a8aa051ef914",
+                "sha256:d3ecfee2ee8d91ab2e08d2d8e89302c729b244e302bbc39c5b5dde42306ff003",
+                "sha256:d5e5be93e1714a59a535bbbc086b9e4fd2448c7547c5288548f6fd86353cad9e",
+                "sha256:de5806be66c9108e4dcdaced084e8ceae14100aa559e2d57b4f0cceb98c462de",
+                "sha256:f49755684a963731479ff3035d45a8185545b4c9f662d368bd349c419839886d",
+                "sha256:fc712a90401bcbf3fa25747f189d6dcfccbecc32712701cad25c6355589dac57"
+            ],
+            "version": "==22.1.0"
         },
         "qtconsole": {
             "hashes": [
-                "sha256:4a38053993ca2da058f76f8d75b3d8906efbf9183de516f92f222ac8e37d9614",
-                "sha256:c091a35607d2a2432e004c4a112d241ce908086570cf68594176dd52ccaa212d"
+                "sha256:12c734494901658787339dea9bbd82f3dc0d5e394071377a1c77b4a0954d7d8b",
+                "sha256:3a2adecc43ff201a08972fb2179df22e7b3a08d71b9ed680f46ad1bfd4fb9132"
             ],
-            "version": "==5.0.3"
+            "version": "==5.1.0"
         },
         "qtpy": {
             "hashes": [
@@ -1604,24 +1595,24 @@
         },
         "six": {
             "hashes": [
-                "sha256:30639c035cdb23534cd4aa2dd52c3bf48f06e5f4a941509c8bafd8ce11080259",
-                "sha256:8b74bedcbbbaca38ff6d7491d76f2b06b3592611af620f8426e82dddb04a5ced"
+                "sha256:1e61c37477a1626458e36f7b1d82aa5c9b094fa4802892072e49de9c60c4c926",
+                "sha256:8abb2f1d86890a2dfb989f9a77cfcfd3e47c2a354b01111771326f8aa26e0254"
             ],
-            "version": "==1.15.0"
+            "version": "==1.16.0"
         },
         "terminado": {
             "hashes": [
-                "sha256:261c0b7825fecf629666e1820b484a5380f7e54d6b8bd889fa482e99dcf9bde4",
-                "sha256:430e876ec9d4d93a4fd8a49e82dcfae0c25f846540d0c5ca774b397533e237e8"
+                "sha256:048ce7b271ad1f94c48130844af1de163e54913b919f8c268c89b36a6d468d7c",
+                "sha256:46fd07c9dc7db7321922270d544a1f18eaa7a02fd6cd4438314f27a687cabbea"
             ],
-            "version": "==0.9.3"
+            "version": "==0.10.0"
         },
         "testpath": {
             "hashes": [
-                "sha256:60e0a3261c149755f4399a1fff7d37523179a70fdc3abdf78de9fc2604aeec7e",
-                "sha256:bfcf9411ef4bf3db7579063e0546938b1edda3d69f4e1fb8756991f5951f85d4"
+                "sha256:1acf7a0bcd3004ae8357409fc33751e16d37ccc650921da1094a86581ad1e417",
+                "sha256:8044f9a0bab6567fc644a3593164e872543bb44225b0e24846e2c89237937589"
             ],
-            "version": "==0.4.4"
+            "version": "==0.5.0"
         },
         "toml": {
             "hashes": [
@@ -1685,48 +1676,48 @@
         },
         "typed-ast": {
             "hashes": [
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-                "sha256:85f95aa97a35bdb2f2f7d10ec5bbdac0aeb9dafdaf88e17492da0504de2e6400",
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-                "sha256:9044ef2df88d7f33692ae3f18d3be63dec69c4fb1b5a4a9ac950f9b4ba571606",
-                "sha256:963c80b583b0661918718b095e02303d8078950b26cc00b5e5ea9ababe0de1fc",
-                "sha256:987f15737aba2ab5f3928c617ccf1ce412e2e321c77ab16ca5a293e7bbffd581",
-                "sha256:9ec45db0c766f196ae629e509f059ff05fc3148f9ffd28f3cfe75d4afb485412",
-                "sha256:9fc0b3cb5d1720e7141d103cf4819aea239f7d136acf9ee4a69b047b7986175a",
-                "sha256:a2c927c49f2029291fbabd673d51a2180038f8cd5a5b2f290f78c4516be48be2",
-                "sha256:a38878a223bdd37c9709d07cd357bb79f4c760b29210e14ad0fb395294583787",
-                "sha256:b4fcdcfa302538f70929eb7b392f536a237cbe2ed9cba88e3bf5027b39f5f77f",
-                "sha256:c0c74e5579af4b977c8b932f40a5464764b2f86681327410aa028a22d2f54937",
-                "sha256:c1c876fd795b36126f773db9cbb393f19808edd2637e00fd6caba0e25f2c7b64",
-                "sha256:c9aadc4924d4b5799112837b226160428524a9a45f830e0d0f184b19e4090487",
-                "sha256:cc7b98bf58167b7f2db91a4327da24fb93368838eb84a44c472283778fc2446b",
-                "sha256:cf54cfa843f297991b7388c281cb3855d911137223c6b6d2dd82a47ae5125a41",
-                "sha256:d003156bb6a59cda9050e983441b7fa2487f7800d76bdc065566b7d728b4581a",
-                "sha256:d175297e9533d8d37437abc14e8a83cbc68af93cc9c1c59c2c292ec59a0697a3",
-                "sha256:d746a437cdbca200622385305aedd9aef68e8a645e385cc483bdc5e488f07166",
-                "sha256:e683e409e5c45d5c9082dc1daf13f6374300806240719f95dc783d1fc942af10"
+                "sha256:01ae5f73431d21eead5015997ab41afa53aa1fbe252f9da060be5dad2c730ace",
+                "sha256:067a74454df670dcaa4e59349a2e5c81e567d8d65458d480a5b3dfecec08c5ff",
+                "sha256:0fb71b8c643187d7492c1f8352f2c15b4c4af3f6338f21681d3681b3dc31a266",
+                "sha256:1b3ead4a96c9101bef08f9f7d1217c096f31667617b58de957f690c92378b528",
+                "sha256:2068531575a125b87a41802130fa7e29f26c09a2833fea68d9a40cf33902eba6",
+                "sha256:209596a4ec71d990d71d5e0d312ac935d86930e6eecff6ccc7007fe54d703808",
+                "sha256:2c726c276d09fc5c414693a2de063f521052d9ea7c240ce553316f70656c84d4",
+                "sha256:398e44cd480f4d2b7ee8d98385ca104e35c81525dd98c519acff1b79bdaac363",
+                "sha256:52b1eb8c83f178ab787f3a4283f68258525f8d70f778a2f6dd54d3b5e5fb4341",
+                "sha256:5feca99c17af94057417d744607b82dd0a664fd5e4ca98061480fd8b14b18d04",
+                "sha256:7538e495704e2ccda9b234b82423a4038f324f3a10c43bc088a1636180f11a41",
+                "sha256:760ad187b1041a154f0e4d0f6aae3e40fdb51d6de16e5c99aedadd9246450e9e",
+                "sha256:777a26c84bea6cd934422ac2e3b78863a37017618b6e5c08f92ef69853e765d3",
+                "sha256:95431a26309a21874005845c21118c83991c63ea800dd44843e42a916aec5899",
+                "sha256:9ad2c92ec681e02baf81fdfa056fe0d818645efa9af1f1cd5fd6f1bd2bdfd805",
+                "sha256:9c6d1a54552b5330bc657b7ef0eae25d00ba7ffe85d9ea8ae6540d2197a3788c",
+                "sha256:aee0c1256be6c07bd3e1263ff920c325b59849dc95392a05f258bb9b259cf39c",
+                "sha256:af3d4a73793725138d6b334d9d247ce7e5f084d96284ed23f22ee626a7b88e39",
+                "sha256:b36b4f3920103a25e1d5d024d155c504080959582b928e91cb608a65c3a49e1a",
+                "sha256:b9574c6f03f685070d859e75c7f9eeca02d6933273b5e69572e5ff9d5e3931c3",
+                "sha256:bff6ad71c81b3bba8fa35f0f1921fb24ff4476235a6e94a26ada2e54370e6da7",
+                "sha256:c190f0899e9f9f8b6b7863debfb739abcb21a5c054f911ca3596d12b8a4c4c7f",
+                "sha256:c907f561b1e83e93fad565bac5ba9c22d96a54e7ea0267c708bffe863cbe4075",
+                "sha256:cae53c389825d3b46fb37538441f75d6aecc4174f615d048321b716df2757fb0",
+                "sha256:dd4a21253f42b8d2b48410cb31fe501d32f8b9fbeb1f55063ad102fe9c425e40",
+                "sha256:dde816ca9dac1d9c01dd504ea5967821606f02e510438120091b84e852367428",
+                "sha256:f2362f3cb0f3172c42938946dbc5b7843c2a28aec307c49100c8b38764eb6927",
+                "sha256:f328adcfebed9f11301eaedfa48e15bdece9b519fb27e6a8c01aa52a17ec31b3",
+                "sha256:f8afcf15cc511ada719a88e013cec87c11aff7b91f019295eb4530f96fe5ef2f",
+                "sha256:fb1bbeac803adea29cedd70781399c99138358c26d05fcbd23c13016b7f5ec65"
             ],
             "markers": "implementation_name == 'cpython' and python_version < '3.8'",
-            "version": "==1.4.2"
+            "version": "==1.4.3"
         },
         "typing-extensions": {
             "hashes": [
-                "sha256:7cb407020f00f7bfc3cb3e7881628838e69d8f3fcab2f64742a5e76b2f841918",
-                "sha256:99d4073b617d30288f569d3f13d2bd7548c3a7e4c8de87db09a9d29bb3a4a60c",
-                "sha256:dafc7639cde7f1b6e1acc0f457842a83e722ccca8eef5270af2d74792619a89f"
+                "sha256:0ac0f89795dd19de6b97debb0c6af1c70987fd80a2d62d1958f7e56fcc31b497",
+                "sha256:50b6f157849174217d0656f99dc82fe932884fb250826c18350e159ec6cdf342",
+                "sha256:779383f6086d90c99ae41cf0ff39aac8a7937a9283ce0a414e5dd782f4c94a84"
             ],
             "markers": "python_version < '3.8'",
-            "version": "==3.7.4.3"
+            "version": "==3.10.0.0"
         },
         "ujson": {
             "hashes": [
@@ -1757,10 +1748,10 @@
         },
         "virtualenv": {
             "hashes": [
-                "sha256:49ec4eb4c224c6f7dd81bb6d0a28a09ecae5894f4e593c89b0db0885f565a107",
-                "sha256:83f95875d382c7abafe06bd2a4cdd1b363e1bb77e02f155ebe8ac082a916b37c"
+                "sha256:14fdf849f80dbb29a4eb6caa9875d476ee2a5cf76a5f5415fa2f1606010ab467",
+                "sha256:2b0126166ea7c9c3661f5b8e06773d28f83322de7a3ff7d06f0aed18c9de6a76"
             ],
-            "version": "==20.4.3"
+            "version": "==20.4.7"
         },
         "wcwidth": {
             "hashes": [
diff --git a/requirements.txt b/requirements.txt
index 63a2770..fe5b2ef 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,64 +1,65 @@
 -i https://pypi.org/simple/
 antimony==2.12.0.3
 appdirs==1.4.4
-attrs==20.3.0
+attrs==21.2.0
 backcall==0.2.0
 cayenne==1.0.3
-certifi==2020.12.5
+certifi==2021.5.30
 chardet==4.0.0
 click==7.1.2
 cycler==0.10.0
-cython==0.29.22
-decorator==4.4.2
+cython==0.29.23
+decorator==5.0.9
 idna==2.10
-importlib-metadata==3.7.3 ; python_version < '3.8'
+importlib-metadata==4.5.0 ; python_version < '3.8'
 iniconfig==1.1.1
-ipykernel==5.5.0
+ipykernel==5.5.5
 ipython-genutils==0.2.0
 ipython==7.16.1
 jedi==0.18.0
-jinja2==2.11.3
-jupyter-client==6.1.12
+jinja2==3.0.1
+jupyter-client==6.2.0
 jupyter-core==4.7.1
 kiwisolver==1.3.1
 libroadrunner==2.0.5
-markupsafe==1.1.1
+markupsafe==2.0.1
 matplotlib==3.3.4
+nest-asyncio==1.5.1
 numpy==1.19.3
 packaging==20.9
 pandas==1.1.5
-parso==0.8.1
+parso==0.8.2
 pexpect==4.8.0 ; sys_platform != 'win32'
 phrasedml==1.1.1
 pickleshare==0.7.5
-pillow==8.1.1
+pillow==8.2.0
 plotly==4.14.3
 pluggy==0.13.1
-prompt-toolkit==3.0.17
+prompt-toolkit==3.0.18
 ptyprocess==0.7.0
 py==1.10.0
-pygments==2.8.1
+pygments==2.9.0
 pyparsing==2.4.7
-pytest==6.2.2
+pytest==6.2.4
 python-dateutil==2.8.1
-python-libcombine==0.2.10
-python-libnuml==1.1.3
+python-libcombine==0.2.11
+python-libnuml==1.1.4
 python-libsbml==5.19.0
-python-libsedml==2.0.15
+python-libsedml==2.0.20
 pytz==2021.1
-pyzmq==22.0.3
+pyzmq==22.1.0
 requests==2.25.1
 retrying==1.3.3
 rrplugins==2.0.5
 sbml2matlab==1.2.3.1
 scipy==1.5.4
 seaborn==0.11.1
-six==1.15.0
+six==1.16.0
 tellurium==2.2.0
 toml==0.10.2
 tornado==6.1
 traitlets==4.3.3
-typing-extensions==3.7.4.3 ; python_version < '3.8'
-urllib3==1.26.4
+typing-extensions==3.10.0.0 ; python_version < '3.8'
+urllib3==1.26.5
 wcwidth==0.2.5
 zipp==3.4.1